MXD Blood Test : Normal Range, Low And High Levels (2025)

The mxd blood test stands for Mixed Cell Count, and it forms a part of a complete blood count test or a WBC differential count. A major portion of the complete blood count consists of the measurement of the concentration of white blood cells, red blood cells, and the platelets in blood while a white blood cell (WBC) count is used to measure the number of white blood cells in the blood and a WBC differential count helps determine the percentage of each type of white blood cell present in the blood.

The Different Types Of WBCs And The MXD Blood Test

The white blood cells (WBCs) are also known as leukocytes and form an important part of the body’s immune system. They’re mainly responsible for protecting the body against infections and invading organisms such as bacteria and viruses. There are mainly five types of white blood cells in the body, and these are;

  1. Neutrophils: These cells form the first line of defense when an infection strikes the body, and they are responsible for killing and digesting bacterial and fungal cells.
  2. Lymphocytes: These white blood cells are responsible for creating antibodies in the body, to defend it against bacteria, viruses, and other harmful invaders.
  3. Monocytes: These cells help break down bacteria.
  4. Basophils: These cells are responsible for the allergic reaction in the body as they secrete chemicals such as histamine when infectious agents enter the body and thus help control the body’s immune response.
  5. Eosinophils: The eosinophils work by attacking and killing parasites, destroying cancer cells, and set off allergic responses in the body as a reaction to allergens.

Out of the five types of white blood cells, the neutrophils and lymphocytes are considered the most important, and their levels are measured separately in a differential WBC count, and the levels of the remaining three types of white blood cells, i.e., the monocytes, eosinophils, and the basophils are sometimes measured together in an MXD blood test.

What Is MXD In CBC?

The complete blood count (CBC), is a broad screening test used by doctors to determine a person’s general health status. The test measures many important values related to the blood cells and generally includes;

  • The white blood cell count
  • The white blood cell differential count including the MXD blood test value
  • The red blood cell count
  • Hematocrit, which is the measure of the proportion of the RBCs to the fluid component of the blood called the plasma
  • The hemoglobin percentage
  • The Mean Corpuscular Volume (MCV)
  • The Mean Corpuscular Haemoglobin (MCH)
  • The Mean Corpuscular Haemoglobin Concentration(MCHC)
  • The Red Cell Distribution Width (RDW)
  • The Platelet Count
  • The Mean Platelet Volume (MPV)

The main components of the CBC are the WBC, RBC, and platelets’ count, and the other components portray the characteristics of these cells, such as their size, color, maturity, and function.

The normal range for the WBC count is between 4,300 and 11000 cells per cubic millimeter of blood. A normal RBC count is generally considered to be between 4.2 to 5.9 million cells per cubic millimeter of blood, and the normal range for the platelet count is considered to be between 150,000 to 400,000 cells per cubic millimeter of blood.

The complete blood count test is mainly used by doctors to evaluate a patient’s overall health, as mentioned earlier, and to detect a wide range of disorders that include anemia, systemic infection or the infection of a specific part of the body, and even leukemia. An abnormal rise or fall in the specific cell counts indicate an underlying disease that may call for further evaluation.

MXD In Blood Test

As mentioned earlier, the MXD blood test is performed as part of a CBC or WBC count or differential WBC count.

So, the preparation for the test is the same as it is for the aforementioned tests. Your doctor may ask you to stop taking certain medications such as over-the-counter supplements and vitamins for a few weeks before your blood sample is collected, as these medications might affect the test results. And there is no need to fast before the test.

The test is performed by obtaining a few millimeters of blood from the patient. The blood sample is usually collected in a lab by a lab technician. The blood sample is drawn from a vein present either at the bend of the arm or in the hand. Before collecting the blood sample, the technician cleans the skin over the vein from which the sample is to be obtained, with an alcohol pad, and a needle is inserted into the vein. The blood is then pulled from the vein through the syringe and collected in a clean vial. The blood sample is then sent for analysis.

What Is MXD% In Blood?

MXD% in the blood is a mixed cell percentage in the blood. There is a certain % of each cell type in the blood that is considered to be normal. If those proportions are out of order, your mxd% increases. A percent breakdown of each cell type tells what the exact problem is.

MXD Normal Range

The MXD blood test also referred to as the Mixed Cell Count Blood Test, is the collective measurement of the levels of the three types of white blood cells which are less significant than the neutrophils and lymphocytes. The test, therefore, measures the combined levels of monocytes, eosinophils, basophils in the blood. The results are expressed as mxd%, and the MXD normal range for a blood test value is considered to be between 5% to 10%.

What Does Low or High MXD Blood Test Mean?

As earlier mentioned, white blood cells form an important part of the immunity system in the body. Usually, a differential WBC count along with a physical examination is enough for a doctor to diagnose any underlying disease leading to the abnormal WBC levels.

High MXD blood means an immune response to an inflammatory condition in the body. The monocytes, eosinophils, and basophils have specific functions to perform in case of the presence of foreign bodies such as bacteria, allergens, parasites, or cancer cells in the body, and an increased MXD in blood test indicates that the immune system is reacting to one of these foreign bodies, and may indicate certain diseases such as asthma, arthritis, leukemia, or tuberculosis.

A low MXD blood test value indicates impaired immunity in the body caused by certain diseases such as cancer, HIV, bone marrow disease/ disorder, lymphoma, lupus, or severe infections.

Medically Reviewed By

Dr. Kaushal M. Bhavsar (MBBS, MD)Assistant Professor in Pulmonary Medicine, GMERS Medical College, Ahmedabad

MXD Blood Test : Normal Range, Low And High Levels (1)

Sushma Hegde

I am an experienced Medical/Scientific writer with a passion for helping people live a happy healthy life. My thirst for writing has followed me throughout the years – it is there when I wake up, lingering at the edges of my consciousness during the day, and teases me at night as I go to sleep.

MXD Blood Test : Normal Range, Low And High Levels (2025)

FAQs

MXD Blood Test : Normal Range, Low And High Levels? ›

Optimal Result: 0 - 12 %. In a complete blood count (CBC) the MXD # refers to the combined count of mixed white blood cells which includes monocytes, eosinophils and basophils.

What does it mean if mxd% is high? ›

A significant rise in the percentage count of MXD is an indication of a corresponding rise in eosinophils, monocytes, and basophils. This may lead to a general immunological response as a number of systems employing antibodies were evoked to disturb the schistosomes [19].

What is the normal range for MXD? ›

In normal adults, the MXD population will primarily consist of monocytes as the normal reference ranges for mono- cytes, basophils and eosinophils are 0.2–1.0 9 109 cells/l, 0.02–0.1 9 109 cells/l and 0.2–0.5 9 109 cells/l, respec- tively.

What does high monocytes and low white blood cells mean? ›

Symptoms and Causes

A high monocyte count is a potential sign of many different medical conditions. It's often linked to infectious diseases like mononucleosis or an autoimmune disease like lupus. Some medications can cause monocytosis. It's also linked to conditions such as blood disorders and certain cancers.

What is low monocytes relative in blood test? ›

Low monocyte levels may mean your body is more susceptible to infection. You may also have low absolute monocytes if your white blood cell count is low. Causes of a low white blood cell count can include: infection. certain medications, including chemotherapy.

Should I be worried if my monocytes are high? ›

Monocytes are a type of white blood cell that helps fight infections in your body. A high monocyte level may indicate inflammation, infection, blood disorders, and other health issues. Along with other types of white blood cells, monocytes are a key element of your immune response.

What is the meaning of MXD? ›

Myxomatous degenerative disease (MXD) is a heart condition that can cause mitral valve prolapse, also known as “floppy valve.” MXD affects the connective tissue in your heart valves.

What is the range of monocytes in leukemia? ›

Features of chronic myelomonocytic leukemia

People with CMML may have shortages of some blood cells, but a main problem is too many monocytes (at least 500 per mm3). Often, the monocyte count is much higher, causing their total white blood cell count to become very high as well.

What is the abnormal range of monocytes? ›

A normal monocyte count is between 2% and 8% of your white blood cell count. This equals about 200 to 800 monocytes per microliter of blood in healthy adults. If your monocyte count is outside those ranges, you're at risk of acquiring a monocyte-related condition.

What happens if MCH is low? ›

The normal range for MCH is 27 to 31 picograms per cell. Anything above or below that may indicate an underlying condition, usually a type of anemia. Low levels of MCH can indicate iron-deficiency anemia while high levels of MCH can signal anemia caused by low levels of folic acid or vitamin B12.

What cancers are linked to high monocytes? ›

The most common sign of chronic myelomonocytic leukemia (CMML) is having too many monocytes (a type of white blood cell), which is seen on a blood test. Having too many monocytes also causes many of the symptoms of CMML. These monocytes can settle in the spleen or liver, enlarging these organs.

Can anxiety cause high monocytes? ›

The researchers observed that the number of circulating neutrophils and monocytes was positively correlated with perceived stress.

What autoimmune diseases cause high monocytes? ›

Causes of High Monocytes
  • Autoimmune and inflammatory diseases, including lupus, rheumatoid arthritis, ulcerative colitis, and inflammatory bowel disease.
  • Bone marrow recovery.
  • Certain cancers, such as leukemia and lymphoma.
  • Chronic infections, including tuberculosis, malaria, and endocarditis.
  • Chronic stress.
  • Depression3.
Jul 25, 2024

What is MXD in a blood test? ›

In a complete blood count (CBC) the MXD # refers to the combined count of mixed white blood cells which includes monocytes, eosinophils and basophils.

Can low monocytes cause fatigue? ›

In monocytopenia, the number of monocytes circulating in the blood is decreased to less than 0.2×109/L in adults. Monocytopenia itself does not appear to produce symptoms, and patients usually only show symptoms related to an associated condition. Such symptoms may include fatigue and fever [1, 2].

What vitamin deficiency causes high monocytes? ›

Increased monocyte-platelet aggregates and monocyte-endothelial adhesion in healthy individuals with vitamin D deficiency.

What cancers cause high absolute monocytes? ›

High monocyte levels can mean leukemia, but not always. You can also have high monocytes when you are recovering from an infection such as tuberculosis or endocarditis, an infection of the heart valve.

Can high monocytes mean heart disease? ›

Overall, monocytes have been used as indicators of prognosis in humans, with their high numbers being associated with increased risk of recurrent MI, hospitalization, and cardiac death.

What medications can cause high monocytes? ›

Monocytosis may be seen in patients receiving cytokines (GM-CSF, M-CSF) TNF-alpha or drugs that increase levels of IL- 3, IL-6, or IL-1. It has also been described in patients taking Olanzapine, allopurinol, corticosteroids, and Griseofulvin.

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